Hello.
I found that Kodi has an issue with some USB DACs with Gpu acceleration for resampling. Try change the resampling to anything else, stop and play your music again and see if it starts working. (try low quality resampling to test if this is the problem). If it does, I’ve put a post together External USB audio, hiss and clicking sound - #16 by Maz with how i fixed it for mine (lots of external links and stuff).
Good luck.
Maz