So, we did some testing here… The good news: everything’s fine with our OSMC skin. The bad news: this is quite a bad Kodi bug.
If we set other skins than our OSMC skin (like Estuary and Confluence) in master and second profile, these things happen:
Either Estuary is somehow loaded although Confluence is selected…
…or Confluence is loaded, but without text.
What is noticable as well: Kodi crashes quite often when switching between profiles - on OSMC as well as on Windows.
Our recommendation: don’t use profiles atm and stick to the master profile. This is an upstream Kodi bug.