Horrible wireless mouse lag after first OSMC install on raspberry pi 3

Well I think you should define “slight delay” clearly the Pi3 is not a power monster and the Kodi GUI is quite demanding. So it might feel a bit sluggish for new users.
With the mouse that is a different topic. The mouse movement itself shouldn’t be to sluggish.
Maybe provide logs either via MyOSMC or command line grab-logs -A so that we can advice