My setup has all my content on a Synology NAS with playback handled by the Vero 4k+, all wired gigabit LAN. The NAS runs PlexMediaServer and Vero 4k+ runs the (ancient) Plex addon.
edit
I shouldn’t say I’ve disabled transcoding, rather I’ve set Plex for Kodi to playback Original quality/Direct Play.
The Vero 4k+ does Direct Play for all my high-bitrate content just fine. I have a resume issue for 4K media which I have a support ticket and Sam is looking at it (fingers crossed!), but playback isn’t an issue.
Example below:
